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Specifieke Transcriptiefactoren Beïnvloeden de Differentiatie van CD8+ T-cellen
CD8⁺ T-cellen, ook wel cytotoxische T-cellen genoemd, zijn een van de belangrijkste wapens van het adaptieve immuunsysteem. Ze herkennen en doden geïnfecteerde cellen en kankercellen en spelen daarmee een cruciale rol in de bescherming tegen virussen en tumoren. Na activatie kunnen deze cellen zich vermenigvuldigen en differentiëren in verschillende functionele toestanden, afhankelijk van signalen uit […]

Aanbevolen

De biomechanica van LSC’s: nieuwe kansen voor gerichte AML-therapie
Acute myeloïde leukemie (AML) blijft een van de meest uitdagende bloedkankers. Ondanks therapeutische vooruitgang blijft de prognose voor veel patië...
Artrose
Verschillende HLA-allelen kunnen bijdragen aan de anti-citrulline-epitoopreactiviteit bij reumatoïde artritis
Reumatoïde artritis (RA) is een chronische auto-immuunziekte die voornamelijk de gewrichten aantast, maar ook systemische effecten kan hebben, bijvoo...

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Immunologie nieuws

Infectieziekten

MDL

Trends in Hepatitis B, Hepatitis C, and HIV Seroprevalence in the Netherlands: Insights From Two Decades of Nationwide PIENTER Serosurveys
Hepatitis B (HBV), hepatitis C (HCV), and HIV remain public health challenges despite effective treatments and preventive options. Infections are ofte...
Nationwide Socioeconomic Evaluation of Direct?Acting Antivirals for Chronic Hepatitis C Virus Infection in Japan Between 2014 and 2023
Interferon-free direct-acting antivirals (DAAs), which are highly effective in eliminating hepatitis C virus (HCV), became available in Japan in 2014....
Droplet Digital PCR Measurement of HBV DNA in On?Treatment Chronic HBV Patients: Association With HCC Development and Outcomes
onlinelibrary.wiley.com
Low-level residual viremia can be present in chronic hepatitis B (CHB) patients on nucleos(t)ide analogues (NUCs). Due to the detection limits of curr...
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Respiratoir systeem

Incidence, Complications, and Quality of Life in Adults ??60?Years Old With Laboratory?Confirmed RSV Infections Attended in Primary Care and in Hospitals: A Study Over Three Seasons in Valladolid, Spain
Respiratory syncytial virus (RSV) infection in adults ??60?years significantly affects health, particularly in those with comorbidities. Despite evide...
Applying the Moving Epidemic Method to Emergency Department Syndromic Surveillance to identify the Start of Influenza Seasons in New South Wales, Australia
The Moving Epidemic Method (MEM) is a widely used threshold-based approach for identifying the start of an influenza season but has rarely been used w...
Symptom probability increases at low pollen exposure in adolescents with allergic rhinitis findings from the GINIplus and LISA birth cohorts
Pollen-induced allergic rhinitis increases significantly with age among children and adolescents and is associated with reduced quality of life due to...
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SOA

M
Anal cancer screening: introduction into routine clinical care for key populations
sti.bmj.com
 Squamous cell carcinoma (SCC) of the anal canal has been increasing globally and disproportionately impacts certain key populations.1 In 2024, the I...
M
Knowledge, attitudes and behaviours in relation to doxycycline post-exposure prophylaxis use among attendees and healthcare workers at two sexual health services in Ireland
sti.bmj.com
Doxycycline post-exposure prophylaxis (doxyPEP) has been shown to reduce syphilis and chlamydia incidence among gay, bisexual and other men who have s...
M
Seek and you shall find! Prevalence and trends of chlamydial and gonococcal infections in a high-density urban area in Italy around the COVID era: a laboratory-based survey
sti.bmj.com
A comprehensive understanding of the epidemiology of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections is essential for developing ...
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