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De expertise van Alexander Hoischen ligt op het grensvlak van genetica en immunologie: daar onderzoekt hij het DNA van patiënten met zeldzame erfelijke afweerstoornissen. Bij een verdenking op een genetische oorzaak, duikt Hoischen in het DNA, op zoek naar een foutje. Hoischen: ‘Ik vind het mooi dat ik werk aan verschillende aandoeningen, waar vaak nog […]
Inleiding Carbapenem-resistente Acinetobacter baumannii (CRAB) heeft zich wereldwijd ontwikkeld tot een belangrijk pathogeen met beperkte behandelopti...
Post-COVID De meerderheid van de mensen die besmet zijn met het SARS-CoV-2 herstelt binnen enkele weken. Er is echter een kleine groep die post-COVID ...
Inhaled allergen challenges (IAC) have been utilised as tools to understand the clinical, physiological and pathobiological responses to allergens in ...
Benralizumab induces rapid and near-complete depletion of eosinophils from blood and lung tissue. We investigated whether benralizumab could attenuate...
We read with great interest the article by Inkster et al. [1] on the positive impact of implementing a waterless intensive care unit (ICU) on the incidence of healthcare-associated water-borne infections (HAWI). The role of the water from sinks and drains in healthcare-associated infections has gained significant attention in recent years due to the emergence of multidrug-resistant infections in the ICU, mainly driven by Pseudomonas aeruginosa [2–4]. In fact, in our hospital we implemented such intervention in 2019 due to a VIM-producing Pseudomonas aeruginosa outbreak.
Febrile neutropenia (FN) is one of the most common complications of stem cell transplantation. The aim of this analysis was to evaluate the frequency of sepsis in patients with FN colonized with resistant Gram negative bacteria (Extended spectrum ?-lactamase positive, multidrug resistant (MDR) P. aeruginosa) and the choice of primary antibiotic in colonized patients.
The aim of this study was to evaluate the effectiveness and safety of the nine most widely studied Vonoprazan (VPZ)-based treatment regimens along with traditional Proton pump inhibitor (PPI)-based treatment r...
Rates of antimicrobial-resistant Helicobacter pylori infection are rising globally, but little is known about contemporary resistance patterns, virule...
Inhaled allergen challenges (IAC) have been utilised as tools to understand the clinical, physiological and pathobiological responses to allergens in ...
The nonspecific interstitial pneumonia (NSIP) pattern is a usual feature of interstitial lung disease (ILD) associated with connective tissue diseases...
Benralizumab induces rapid and near-complete depletion of eosinophils from blood and lung tissue. We investigated whether benralizumab could attenuate...
Long COVID (also known as "post-acute sequelae of COVID-19") is a multi-system disorder that follows an acute bout of severe acute respiratory syndrom...
Merck, known as MSD outside of the United States and Canada, announced positive top─line results from its pivotal phase 3 trial (V503─064) evaluating the company's 9─valent Human Papillomavirus
Chlamydia trachomatis is classified into 15 major genotypes, A to L3, based on the diversity of ompA gene. Here, we evaluated and characterised the di...
GSK plc announced that it has completed the primary objective data analysis from the phase II part of the TH HSV REC─003 trial. This trial is a combined phase I/II proof─of─concept study to assess potential clinical