COVID
Alexander Hoischen benoemd tot hoogleraar Genomic technologies for immune-mediated and infectious diseases
De expertise van Alexander Hoischen ligt op het grensvlak van genetica en immunologie: daar onderzoekt hij het DNA van patiënten met zeldzame erfelijke afweerstoornissen. Bij een verdenking op een genetische oorzaak, duikt Hoischen in het DNA, op zoek naar een foutje. Hoischen: ‘Ik vind het mooi dat ik werk aan verschillende aandoeningen, waar vaak nog […]

Aanbevolen

Infectieziekten
Een nieuwe antibioticaklasse ontdekt voor resistente bacterie
Inleiding Carbapenem-resistente Acinetobacter baumannii (CRAB) heeft zich wereldwijd ontwikkeld tot een belangrijk pathogeen met beperkte behandelopti...
COVID
Oorzaak van aanhoudende vermoeidheid bij post-COVID
Post-COVID De meerderheid van de mensen die besmet zijn met het SARS-CoV-2 herstelt binnen enkele weken. Er is echter een kleine groep die post-COVID ...

Immunologie nieuws

Allergie

M
Allergen challenge, eosinophils and the long road to asthma endotypes
erj.ersjournals.com
Inhaled allergen challenges (IAC) have been utilised as tools to understand the clinical, physiological and pathobiological responses to allergens in ...
M
Benralizumab for allergic asthma: a randomised, double-blind, placebo-controlled trial
erj.ersjournals.com
Benralizumab induces rapid and near-complete depletion of eosinophils from blood and lung tissue. We investigated whether benralizumab could attenuate...
Toon meer

Infectieziekten

Parents' transplant plea: 'One more infection and we could lose our boy'
bbc.com
Two-year-old Zachary Bradford could die in weeks if a donor cannot be found.
Collateral damages of a waterless intensive care unit
We read with great interest the article by Inkster et al. [1] on the positive impact of implementing a waterless intensive care unit (ICU) on the incidence of healthcare-associated water-borne infections (HAWI). The role of the water from sinks and drains in healthcare-associated infections has gained significant attention in recent years due to the emergence of multidrug-resistant infections in the ICU, mainly driven by Pseudomonas aeruginosa [2–4]. In fact, in our hospital we implemented such intervention in 2019 due to a VIM-producing Pseudomonas aeruginosa outbreak.
Toon meer

MDL

Efficacy and safety of Vonoprazan-based treatment of Helicobacter pylori infection: a systematic review and network meta-analysis
The aim of this study was to evaluate the effectiveness and safety of the nine most widely studied Vonoprazan (VPZ)-based treatment regimens along with traditional Proton pump inhibitor (PPI)-based treatment r...
Genomic analysis of Helicobacter pylori in Australia: Antimicrobial resistance, phylogenetic patterns, and virulence factors
Rates of antimicrobial-resistant Helicobacter pylori infection are rising globally, but little is known about contemporary resistance patterns, virule...
Toon meer

Respiratoir systeem

M
Allergen challenge, eosinophils and the long road to asthma endotypes
erj.ersjournals.com
Inhaled allergen challenges (IAC) have been utilised as tools to understand the clinical, physiological and pathobiological responses to allergens in ...
M
Rituximab and mycophenolate mofetil in interstitial lung disease (EVER-ILD): 1-year follow-up results of a randomised controlled trial
erj.ersjournals.com
The nonspecific interstitial pneumonia (NSIP) pattern is a usual feature of interstitial lung disease (ILD) associated with connective tissue diseases...
M
Benralizumab for allergic asthma: a randomised, double-blind, placebo-controlled trial
erj.ersjournals.com
Benralizumab induces rapid and near-complete depletion of eosinophils from blood and lung tissue. We investigated whether benralizumab could attenuate...
Toon meer

SOA

Merck reports positive top?line results from phase 3 trial evaluating efficacy and safety of Gardasil 9 in Japanese males
pharmabiz.com
Merck, known as MSD outside of the United States and Canada, announced positive top─line results from its pivotal phase 3 trial (V503─064) evaluating the company's 9─valent Human Papillomavirus
M
Distribution of Chlamydia trachomatis ompA-genotypes over three decades in Portugal
sti.bmj.com
Chlamydia trachomatis is classified into 15 major genotypes, A to L3, based on the diversity of ompA gene. Here, we evaluated and characterised the di...
GSK announces phase I/II therapeutic herpes simplex virus vaccine trial fails to meet the study's primary efficacy objective
pharmabiz.com
GSK plc announced that it has completed the primary objective data analysis from the phase II part of the TH HSV REC─003 trial. This trial is a combined phase I/II proof─of─concept study to assess potential clinical
Toon meer