Journal of Cerebral Blood Flow &Metabolism, Ahead of Print. Asymptomatic carotid artery stenosis (aCAS) increases the risk of ischemic stroke despite lacking clinical symptoms. This study sought to characterize the serum metabolic profile of aCAS and to identify potential biomarkers associated with plaque ...

Journal of Cerebral Blood Flow &Metabolism, Ahead of Print.

Journal of Cerebral Blood Flow &Metabolism, Ahead of Print. Cerebral amyloid angiopathy (CAA) is a small vessel disease associated with hemorrhagic lesions including microbleeds and intracerebral hemorrhage. Growing evidence suggests vascular remodeling may be a critical step leading to CAA-related vessel rupture. ...

Source: Neuropharmacology

Publication date: Available online 28 February 2026

Publication date: Available online 23 February 2026

Publication date: Available online 23 February 2026

Despite the ongoing controversy around the prophylactic use of antiseizure medications (ASMs) in seizure-naïve patients undergoing brain tumor surgery, this practice has persisted for years. This study aims to develop and validate a machine-learning framework for stratifying postoperative seizure risk.

Publication date: Available online 21 January 2026

A 62-year-old male presented with acute onset headache and intermittent left-sided tinnitus. Non-contrast CT of the brain demonstrated focal subarachnoid hemorrhage within the prepontine cistern as shown in Fig. 1a. Cerebral digital subtraction angiography revealed a broad-based saccular aneurysm of the proximal left anterior inferior cerebellar artery (AICA) associated with a high-flow left petrous dural arteriovenous fistula (DAVF). The DAVF was supplied by multiple feeders from branches of the middle meningeal, accessory meningeal, posterior auricular, and occipital arteries and the left vertebral artery.

Numerous studies have evaluated greater occipital nerve (GON) blockade for migraine prophylaxis using various techniques and anesthetic agents, yet a standardized protocol remains lacking. Although both lidocaine and bupivacaine are effective compared with placebo, no direct comparison exists. This study aimed to compare the efficacy of lidocaine and bupivacaine in GON blockade for chronic migraine.

Multiple sclerosis (MS) is a chronic, immune-mediated disease of the central nervous system characterized by inflammation, demyelination, and neurodegeneration. It is a leading cause of non-traumatic neurological disability in young adults and presents with a heterogeneous range of symptoms, including motor and sensory deficits, cognitive impairment, fatigue, depression, and sleep disturbance, that collectively reduce quality of life and functional independence [1,2].

Data regarding the optimal treatment of infectious intracranial aneurysms remains sparse. With growing utilization of endovascular therapy for cerebrovascular disease, we examined trends in endovascular versus neurosurgical treatment of infectious aneurysms and investigated the impact of treatment modality on outcomes.

Cerebral edema (CE) is the pathological accumulation of excess fluid within the brain parenchyma that causes an increased intracranial volume and, subsequently, pressure. [1] It is a potentially life-threatening response to various primary neurological insults, including ischemic stroke, traumatic brain injury (TBI), brain tumors, infections (i.e., meningitis and encephalitis), metabolic encephalopathies, and hypoxic-ischemic injury. The resulting increase in intracranial pressure compromises cerebral perfusion and causes secondary ischemic damage.

The jugular foramen (JF) is characterized as a bony cranial structure that is formed at the junction of the temporal and occipital bones near the posterior termination of the petro-occipital fissure. This anatomical canal has many structures that can attract the attention of many specialists, such as radiologists and neurosurgeons [1]. Configurations like the bony dome, bony septations depth of the jugular fossa and presence of high jugular bulb, all convey a critical role in surgical operations as well as pathophysiology of several syndromes and manifestations.

Insular glioma (IG) resection is technically demanding and carries a high risk of postoperative neurological deficits, primarily due to ischemic injury to the middle cerebral artery (MCA) perforators. Understanding pre- and postoperative lenticulostriate artery (LSA) anatomy may clarify the tumor-perforator relationship and its clinical impact.

Cerebral edema (CE) is the pathological accumulation of excess fluid within the brain parenchyma that causes an increased intracranial volume and, subsequently, pressure. [1] It is a potentially life-threatening response to various primary neurological insults, including ischemic stroke, traumatic brain injury (TBI), brain tumors, infections (i.e., meningitis and encephalitis), metabolic encephalopathies, and hypoxic-ischemic injury. The resulting increase in intracranial pressure compromises cerebral perfusion and causes secondary ischemic damage.

Despite the ongoing controversy around the prophylactic use of antiseizure medications (ASMs) in seizure-naïve patients undergoing brain tumor surgery, this practice has persisted for years. This study aims to develop and validate a machine-learning framework for stratifying postoperative seizure risk.