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Traditionele ICD’s Een defibrillator vermindert sudden arrhythmic death (SUD; plotselinge hartdood) bij patiënten met een risico op aritmieën. Bij de traditionele ICD’s kunnen de lead of leads transveneus of subcutaan worden geplaatst. Aan de transveneuze ICD (T-ICD) implantatie zitten bepaalde risico’s vast, zoals vasculaire verwondingen en obstructies. Transveneuze leads zijn ook onderhevig aan mechanisch falen […]
De afgelopen tien jaar is er opvallende vooruitgang geboekt op het gebied van orgaantransplantatie. Daarom wordt een orgaantransplantatie tegenwoordig...
Accurate stratification of the risk of lymph node metastasis (LNM) following endoscopic resection of submucosal invasive (T1) colorectal cancer (CRC) ...
Reversal of ileostomy is associated with morbidity including wound infection and prolonged wound healing. Negative pressure wound therapy (NPWT) has b...
In this retrospective study of the postoperative outcomes and survival of 111 EOCRC patients treated at the Royal Prince Alfred Hospital in Sydney, Au...
NSW Australia has the highest reported rate of reconstruction (pouch or ileorectal anastomosis) following UC (procto)colectomy globally. However, rate...
Bristol Myers Squibb announced that the US Food and Drug Administration (FDA) approved Opdivo (nivolumab) for the treatment of adult patients with resectable (tumours =4 cm or node positive) non─small cell lung cancer
Patients with brain tumours are motivated to participate in clinical trials involving repeat tissue sampling. Normalising the use of neoadjuvant and staged surgical trials necessitates collaboration among patients, regulatory agencies, and researchers. Initial and repetitive tissue sampling plays a crucial role in enhancing our understanding of resistance mechanisms and vulnerabilities in brain tumour therapy. Standardising biopsy techniques and ensuring technical uniformity across institutions are vital for effective interinstitutional collaboration.
Microvascular dysfunction after heart transplantation leads to restrictive cardiac allograft physiology (RCP), which is classified as severe coronary allograft vasculopathy (CAV); however, the prognosis of RCP remains unclear. Therefore, in this study, we aimed to elucidate the prognosis of RCP in comparison with that of severe angiographic CAV.
A 28-year-old man, who received a two-haplotype matched renal transplant for end-stage renal disease secondary to IgA nephropathy, was evaluated for immunosuppression withdrawal using a novel method to develop delayed immunological tolerance. The kidney had been donated by his brother 14 months earlier. The patient had been maintained on standard triple therapy immunosuppression. A plasma donor-derived cell-free DNA test—obtained 8 months after the initial transplantation—was negative for allograft injury.
Cardiac allografts procured via a donation after circulatory death (DCD) pathway undergo a period of unavoidable global warm ischemia. As a result, prior to 2014, hearts from DCD donors were rarely transplanted and then only when donor and recipient were co-located in adjacent operating theatres. However, the use of normothermic machine perfusion (NMP) device: the Transmedics Organ Care System Heart (OCS Heart, Boston, MA, USA), allowed for the ex-situ assessment of the viability of DCD hearts and subsequent successful transplantation.
Adolescent trauma patients are at increased risk of venous thromboembolism (VTE). It is unclear whether VTE prophylaxis practice patterns differ across trauma center types.
Adolescent trauma patients are at increased risk of venous thromboembolism (VTE). It is unclear whether VTE prophylaxis practice patterns differ across trauma center types.
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