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Oncologie bericht test


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Infectieziekten
Plasmide-DNA: een veelbelovende strategie tegen therapieresistente B-ALL
Ongeveer één op de zes leukemiepatiënten ontwikkelt B-cell acute lymphoblastische leukemie (B-ALL), een agressieve vorm van leukemie die vooral voorkomt bij volwassenen. Zelfs na volledige remissie blijft het risico op terugval groot. Momenteel worden deze patiënten vaak behandeld met de CD3/CD19 bispecifieke T-cell engager (BiTE) antistof Blinatumomab. Deze antistof verbindt twee celtypen met elkaar: het […]

Aanbevolen

Long
Testen in de toekomst: visie op een toekomstbestendige aanpak
dr. A.J. van der Wekken, longarts UMCG De aan- of afwezigheid van bepaalde mutaties kan een enorme impact hebben op het succes van een behandeling. Bi...
Long
Visie en prioriteiten van de EORTC
prof.dr. A.C. Dingemans, longarts Erasmus MC en voorzitter van de EORTC lung cancer group De EORTC is een Europese organisatie, gericht op klinisch en...

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Oncologie nieuws

Borst


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Hoofd-hals

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx
onlinelibrary.wiley.com
University of Michigan Cancer Center (UMCC) protocol 9520 treated stage III/IV locally advanced squamous cell carcinoma of the larynx (LASCCL) with ci...
Differences in Survival Following Surgery Versus Chemoradiotherapy for Clinical Stage T4a Laryngeal Squamous Cell Carcinoma: A Propensity Score?Matched Analysis
onlinelibrary.wiley.com
Although laryngeal cancer incidence has declined in the United States, case fatality has risen. The survival equivalence of surgery versus chemoradiot...
Rates of ICU Delirium After Microvascular Free Tissue Transfer Reconstruction of the Oral Cavity and Oropharynx
onlinelibrary.wiley.com
Microvascular free tissue transfer (MFTT) is the standard in the reconstruction of major head and neck defects, but involves extended hospital stays a...
Toon meer

Long


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MDL

From the Editor’s Desk...
journal-of-hepatology.eu
Alcohol consumption and chronic HBV infection are both well-established risk factors for hepatocellular carcinoma (HCC), yet the molecular mechanisms by which these two insults interact to accelerate carcinogenesis have remained poorly understood. Zhou, Ba and coworkers identify an alcohol-induced ATF4/LPLA2 signalling axis that amplifies lipid species metabolism, thereby creating a pro-tumorigenic metabolic environment in HBV-infected hepatocytes. Disruption of ATF4 or LPLA2 attenuates bis(monoacylglycero)phosphate accumulation, reduces oncogenic signalling, and suppresses tumour formation in experimental models.
Molecular profiling and matched targeted treatment in cholangiocarcinoma: results from the Italian dataset (ANITA)
journal-of-hepatology.eu
Extended molecular profiling (EMP) is recommended to tailor targeted treatment for advanced cholangiocarcinoma (CCA). However, neither the impact of EMP nor the availability of targeted therapies has been extensively described in a real-world setting.
Molecular profiling and matched targeted treatment in cholangiocarcinoma: results from the Italian dataset (ANITA)
journal-of-hepatology.eu
Extended molecular profiling (EMP) is recommended to tailor targeted treatment for advanced cholangiocarcinoma (CCA). However, neither the impact of EMP nor the availability of targeted therapies has been extensively described in a real-world setting.
Toon meer

Pediatrie


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Sarcoom


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