Halloween, 2004 was an actual nightmare for our family. After an evening of trick-or-treating along Newtown, Connecticut’s festive Main Street, we g...

Journal of Child and Adolescent Psychopharmacology, Ahead of Print.

A study issued yesterday in Pediatrics did not identify a causal link between stimulant prescriptions and psychotic experiences (subclinical hallucina...

Halloween, 2004 was an actual nightmare for our family. After an evening of trick-or-treating along Newtown, Connecticut’s festive Main Street, we g...

Antidepressants remain among the most widely used class of drugs in treating bipolar disorder, despite their minimal efficacy in randomized clinical t...

Obsessive–compulsive disorder (OCD) is a debilitating mental health condition that impacts daily functioning. In addition to classical symptoms, emo...

This study aimed to predict suicidal ideation among youth with autism spectrum disorder (ASD) by applying machine learning techniques. A cross-section...

There is no significant difference in the effectiveness of how autistic and non-autistic people communicate, according to a new study, challenging the stereotype that autistic people struggle to connect with others.

Telomir Pharmaceuticals, Inc, a leader in age─reversal science, announced new preclinical data showing that its lead oral drug candidate, Telomir─1, reverses multiple hallmarks of cellular decline across several human cell

Years ago, when I was applying for medical school, I had to go through the usual gyrations of filling out the applications and attending interviews. P...

AbstractBackgroundShared decision-making (SDM) implementation remains limited in psychosis management, particularly within antipsychotic prescribing. When and why prescribers engage in SDM within these contexts is largely unknown. Part 1 of this two-part realist review aimed to understand the impact of structural and contextual factors on prescriber engagement in SDM within antipsychotic prescribing.Study designCINAHL Plus, Cochrane Library, Embase, PsycINFO, PubMed, Scopus, Sociological Abstracts, Web of Science, and Google Scholar were searched for evidence to develop realist program theories outlining the relationship between macro-level contexts and their impact on prescriber behaviors.Study resultsFrom 106 included documents, five program theories explaining relationships between (i) leadership and governance, (ii) workforce development, and (iii) service delivery contexts and their impact on reducing prescriber engagement with behaviors required of SDM application were developed. No facilitative macro-level contexts were identified. Key mechanisms reducing prescriber engagement in desired behaviors include fear of individual blame for adverse outcomes and exposure to liability, pressure from service environments to prioritize decreasing risk of harm, devaluing of experiential knowledge, and beliefs that SDM conflicts with duties of beneficence and non-maleficence.ConclusionEven empirically efficacious interventions will be difficult to implement at scale within real-world settings due to misalignment with complex cultural, legal, and professional realities prominent therein. Mechanisms responsible for reducing prescriber engagement in SDM should be the target of structural interventions necessary to support contextual integration into psychosis management. Part 2 outlines features of service delivery contexts, workforce development, and technology that can increase prescriber engagement in SDM.

AbstractBackgroundShared decision-making (SDM) implementation remains limited in psychosis management, particularly within antipsychotic prescribing. When and why prescribers engage in SDM within these contexts is largely unknown. Part 2 of this 2-part realist review aimed to understand what SDM intervention strategies and local implementation contexts are responsible for successful prescriber engagement and why.Study designCINAHL Plus, Cochrane Library, Embase, PsycINFO, PubMed, Scopus, Sociological Abstracts, Web of Science, and Google Scholar were searched for evidence to develop realist program theories explaining relationships between meso- and micro-level contexts and impact on prescriber behaviors.Study resultsFrom 106 included documents, 5 program theories were developed explaining mechanisms responsible for increasing prescriber engagement with desired behaviors, alongside facilitative features within service delivery contexts and workforce development. Key mechanisms included reducing prescriber fear of sole responsibility for harm, reducing the perceived burden of SDM, increasing prescriber confidence in their ability to productively negotiate treatment consultations and their confidence to safely increase patient autonomy within decision-making. These mechanisms should be the focus of those interested in designing SDM interventions to increase prescriber engagement and those responsible for translating results of effective interventions into real-world settings to ensure facilitative contexts are maintained.ConclusionIntervention strategies that should be prioritized for scale-up include attempting SDM within existing therapeutic relationships, adopting a multidisciplinary team (MDT) responsibility for SDM implementation, and workforce training in skillsets required of effective SDM application. Efforts to standardize psychosis care via MDTs and systematically reduce discontinuity and fragmentation of care are required at policy-level.

Editor’s Note: This article originally appeared on our affiliate site, Mad in the UK. It was written by retired Emergency Physician Cathy Wield, an...

Halloween, 2004 was an actual nightmare for our family. After an evening of trick-or-treating along Newtown, Connecticut’s festive Main Street, we g...

This study aimed to predict suicidal ideation among youth with autism spectrum disorder (ASD) by applying machine learning techniques. A cross-section...

“A disease is a condition that people die from or are physically impaired by. Everything else is a human condition.” —Thomas Szasz

Editor’s Note: This article originally appeared on our affiliate site, Mad in the UK. Jo Watson, psychotherapist and founder of Drop the Disorder! ...

Functional disorders (FDs) benefit from psychotherapy. However, the determinants predicting their efficacy remain largely unexplored.

Years ago, when I was applying for medical school, I had to go through the usual gyrations of filling out the applications and attending interviews. P...

Establishing robust evidence for psychotherapeutic treatment efficacy is crucial in evidence-based medicine for mental disorders. Randomized controlle...

J Clin Psychiatry. 2025 May 21;86(3):24m15462. doi: 10.4088/JCP.24m15462.

Years ago, when I was applying for medical school, I had to go through the usual gyrations of filling out the applications and attending interviews. P...

In many families, traditions are cherished as the glue that binds generations. They’re passed down like heirlooms: recipes, rituals, phrases, and va...