The systems were affected by a hack on the NHS, which caused significant disruption.

The continuous generation of blood cells relies on hematopoietic stem cells (HSCs) and their capacity for both self-renewal and differentiation into all types of blood lineages [1]. Throughout embryonic development, transient hematopoietic sites appear to maintain the supply of required blood cell types. In mice at embryonic day 7.0 (E7.0), primitive hematopoiesis starts in the yolk sac (YS). During the first wave of hematopoiesis, primitive erythroid cells emerge from the blood islands and make the first circulating cells in the blood [2].

The continuous generation of blood cells relies on hematopoietic stem cells (HSCs) and their capacity for both self-renewal and differentiation into all types of blood lineages [1]. Throughout embryonic development, transient hematopoietic sites appear to maintain the supply of required blood cell types. In mice at embryonic day 7.0 (E7.0), primitive hematopoiesis starts in the yolk sac (YS). During the first wave of hematopoiesis, primitive erythroid cells emerge from the blood islands and make the first circulating cells in the blood [2].