Snelle toegang tot veelbelovende geneesmiddelen voor zeldzame ziekten
Het medicijn dat dankzij ODAP vanaf 1 maart beschikbaar is, heet tofersen. Dit is een medicijn tegen een zeldzame erfelijke vorm van ALS, ongeveer 1-2% van de mensen met ALS lijdt aan deze vorm. Obstakels beschikbaarheid nieuwe medicijnen Vaak vormen de hoge kosten en onzekerheid over de (lange termijn) klinische effectiviteit van nieuwe medicijnen een […]

Aanbevolen

Artrose
Oefentherapie voor knieartrose
Knieartrose is een veel voorkomende aandoening die kan leiden tot chronische gewrichtspijn, kniestijfheid, verminderde kniefunctie en verminderde kwal...
Heup
Heupairbags verlagen incidentie heup- en bekkenfracturen bij ouderen
Naar schatting valt een derde van alle patiënten in de leeftijd van > 65 jaar elk jaar, en de helft daarvan valt herhaaldelijk. ‎Als men ouder w...

Orthopedie nieuws

Heup

Unilateral Single Joint Arthritis Changes Joint Power in Unaffected Joints
onlinelibrary.wiley.com
Pain and disability associated with arthritis of the hip, knee, or ankle is well-documented. However, data on joint power and how arthritis in one joi...
Challenges in Meeting Centers for Medicare and Medicaid Services Patient-Reported Outcome Measures Collection Requirements and Patient Predictors of Substantial Clinical Benefit Achievement in Total Joint Arthroplasty
arthroplastyjournal.org
Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are highly effective procedures, with the Centers for Medicare and Medicaid Services (CMS) mandating patient-reported outcome measures (PROMs) for Medicare patients starting July 1, 2024. This study evaluated PROM collection rates and identified predictors of substantial clinical benefit (SCB), defined by CMS as a 22-point improvement in Hip Dysfunction and Osteoarthritis Outcome Score for Joint Replacement (HOOS-JR) for THA and a 20-point improvement in Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR) for TKA at four surgical sites across an academic tertiary referral center.
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Knie

Proteomics Reveals Increased Periostin in Synovial Fluid From Canine and Human Anterior Cruciate Ligament Injury
onlinelibrary.wiley.com
Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved tar...
Unilateral Single Joint Arthritis Changes Joint Power in Unaffected Joints
onlinelibrary.wiley.com
Pain and disability associated with arthritis of the hip, knee, or ankle is well-documented. However, data on joint power and how arthritis in one joi...
Cartilage targeting cationic peptide carriers display deep cartilage penetration and retention in a rabbit model of post-traumatic osteoarthritis
oarsijournal.com
Drug delivery to cartilage is limited by its complex architecture and avascularity. Cationic Peptide Carriers (CPC) have previously been optimized for improved cartilage transport and retention of drugs in vitro. In this study, we evaluated the kinetics, stability, and immunogenicity of CPCs after a single intra-articular injection using a rabbit knee injury model.
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Pediatrie

Neurodevelopmental Outcomes of Very Low Birth Weight Infants Following Extrauterine Placental Perfusion: A Follow?Up Study
onlinelibrary.wiley.com
Extrauterine placental perfusion (EPP) may be a feasible cord clamping strategy in very low birth weight (VLBW) infants to support neonatal transition...
Automated identification of clinically meaningful biomechanical phenotypes in cerebral palsy through multicenter gait data
clinbiomech.com
Cerebral palsy is the most prevalent motor disability in childhood, encompassing various movement disorders that affect walking. Researchers have described gait patterns in cerebral palsy, but these are often subjective and based on clinician experience. This study introduces an automated approach to objectively identify clinically meaningful biomechanical phenotypes in cerebral palsy and test it on multicenter gait data. Utilizing instrumented gait analysis, this research aims to improve treatment strategies for gait dysfunction.
Automated identification of clinically meaningful biomechanical phenotypes in cerebral palsy through multicenter gait data
clinbiomech.com
Cerebral palsy is the most prevalent motor disability in childhood, encompassing various movement disorders that affect walking. Researchers have described gait patterns in cerebral palsy, but these are often subjective and based on clinician experience. This study introduces an automated approach to objectively identify clinically meaningful biomechanical phenotypes in cerebral palsy and test it on multicenter gait data. Utilizing instrumented gait analysis, this research aims to improve treatment strategies for gait dysfunction.
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Sportorthopedie

Kristyna Hargitaiova, DVM
ors.org
Doctor of Veterinary MedicineResearch FellowIncoming PhD Candidate
Safe Activity participation Following Elective Total hip replacement: the SAFE-T investigation
bjsm.bmj.com
Total hip replacement (THR) is one of the most common elective orthopaedic surgeries performed, with increasing demand among younger individuals. Few ...
Rehabilitation after arthroscopic shoulder stabilisation: are we letting patients down by being too conservative?
bjsm.bmj.com
The glenohumeral joint is the most commonly dislocated joint in the body,1 primarily due to sports-related injuries, with up to 15% of contact athlete...
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Wervelkolom

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