Meet the Trialist: Innovating cardiac monitoring with MONITOR-HF
MONITOR-HF The MONITOR-HF trial enrolled 348 participants with class III heart failure, as classified by the New York Heart Association (NYHA), across 25 centres. The participants were randomly assigned to receive standard guideline-directed medical therapy (GDMT) or GDMT plus haemodynamic monitoring using the CardioMEMS HF System. The study's primary endpoint was the change in quality […]


Effect van een SGLT2-remmer op anemie bij nierpatiënten
Anemie komt vaak voor bij patiënten met CKD. Dit wordt toegeschreven aan verminderde erytropoëtinesynthese, ijzerdeficiëntie (absoluut en functione...
De invloed van magnesium op dementie
Onderzoek Deelnemers (40-73 jaar) van de UK Biobank (n = 6001) werden geïncludeerd en gestratificeerd naar geslacht. Mg in de voeding werd ...

Cardiologie nieuws

Is There a Direct Effect Between the Plication of the Myoaponeurotic Layer and the Force of Inspiratory and Expiratory Muscles After Abdominoplasty?
Objective Abdominoplasty may generate an increase in the intra-abdominal pressure (IAP) and consequently an alteration in the pulmonary ventilation. The purpose of this study was to evaluate the potential alterations in the maximal static inspiratory pressure (MIP) and maximal static expiratory pressure (MEP) after abdominoplasty.Methods Thirty-three female patients, aged between 18 and 60, with type III/B Nahas abdominal deformity that underwent abdominoplasty with plication of the anterior rectus and external oblique aponeurosis were selected. The MIP and MEP were measured using a mouthpiece. This is a simple way to indirectly gauge inspiratory and expiratory muscle strength. Measurements were performed before surgery and on the 2nd, 7th, 15th, and 180th postoperative day. In addition, IAP was measured before abdominoplasty and after the placement of compression garment. The MIP and MEP were compared using analysis of variance, followed by the Bonferroni multiple comparison test pairing the different points in time. Paired Student's t test was used for comparing IAP measurements. Pearson's correlation test was used to compare MIP and MEP variations with IAP variation. Results were considered statistically significant when P ? 0.05.Results A decrease was observed in MEP on the 2nd day, with a return close to normal values on the 15th day. In opposition MIP had a surprisingly increase on the 15th postoperative day (129 cmH2O), normalizing 180 days after the operation. A leap in IAP values was revealed at the end of the surgical procedure. It was not possible to establish a positive correlation between the increase of IAP and the alterations of MIP and MEP.Conclusions There is a decrease in maximum expiratory pressure on the very early postoperative day (2nd postoperative day) and an increase in maximum inspiratory pressure on the 15th postoperative day in patients who underwent abdominoplasty. There was no correlation between the IAP and maximum respiratory pressure variations, both inspiratory and expiratory.
Continuous glucose monitoring and the effect of liraglutide in cardiac surgery patients: a sub-study of the randomized controlled GLOBE trial
Firstly, to evaluate the accuracy and reliability of continuous glucose monitoring (CGM) in patients undergoing cardiac surgery and, secondly, to assess the impact of preoperative liraglutide administration on perioperative glucose control as captured by CGM.
Analgesic Effect and Sleep Quality of Low-Dose Dexmedetomidine in Cardiac Surgical Patients After Ultrafast-Track Extubation: A Randomized Clinical Trial
: To compare the analgesic and sleep quality effects of dexmedetomidine infusion versus placebo in patients undergoing cardiac surgery with ultra-fast track extubation.

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