Meet the Trialist: The "Sweet Spot" from RELIEVE-HFThe RELIEVE-HF trial (NCT03499236) evaluated the efficacy of interatrial shunting using the Ventura shunt in heart failure (HF) patients with reduced (HFrEF) and preserved ejection fraction (HFpEF). This global study randomised 508 participants to receive either the shunt or a placebo procedure, alongside optimal medical therapy. The study's primary endpoint – combining mortality, heart transplant […]