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Infectie De belangrijkste route van hiv-1-overdracht naar vrouwen is via het cervicovaginale slijmvlies tijdens geslachtsgemeenschap. Onder niet-inflammatoire omstandigheden verkeren vaginale Langerhans cellen (LC) in een onrijpe staat en beschermen ze tegen infectie via autofagie-gemedieerde degradatie van het virus. Bij activatie van de LC wordt deze antivirale functie aangetast. De geactiveerde LC kunnen worden geïnfecteerd door […]
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